Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol.

@article{Niemann2000IndocyanineGK,
  title={Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol.},
  author={Claus U. Niemann and Thomas K. Henthorn and Tom C. Krejcie and Colin A. Shanks and C Enders-Klein and Michael J. Avram},
  journal={Clinical pharmacology and therapeutics},
  year={2000},
  volume={67 4},
  pages={342-50}
}
BACKGROUND AND OBJECTIVES Although indocyanine green can be used to estimate cardiac output and blood volume independently, a recirculatory multicompartmental indocyanine green model enables description of these and additional intravascular events. Our model was used to describe the effect of propranolol on blood volume and flow distribution in humans. METHODS Indocyanine green disposition was determined twice in four healthy adult men, once during a propranolol infusion that decreased… CONTINUE READING

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