Indocyanine Green-holo-Transferrin Nanoassemblies for Tumor-Targeted Dual-Modal Imaging and Photothermal Therapy of Glioma.

@article{Zhu2017IndocyanineGN,
  title={Indocyanine Green-holo-Transferrin Nanoassemblies for Tumor-Targeted Dual-Modal Imaging and Photothermal Therapy of Glioma.},
  author={Mingting Zhu and Zonghai Sheng and Yali Jia and Dehong Hu and Xin Liu and Xianyuan Xia and Chengbo Liu and Pan Wang and Xiaobing Wang and Hairong Zheng},
  journal={ACS applied materials & interfaces},
  year={2017},
  volume={9 45},
  pages={
          39249-39258
        }
}
Active-targeted cancer imaging and therapy of glioma has attracted much attention in theranostic nanomedicine. As a promising tumor-targeting ligand, holo-transferrin (holo-Tf) has been applied for enhancing delivery of nanotheranostics. However, holo-Tf-based nanoassemblies for active targeting mediated multimodal imaging and therapeutics have not been previously reported. Here, we develop a one-step method for the preparation of holo-Tf-indocyanine green (holo-Tf-ICG) nanoassemblies for… CONTINUE READING

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