Individualizing the risk for preterm birth: an overview of the literature

  title={Individualizing the risk for preterm birth: an overview of the literature},
  author={M. V. Os and J. Ven and B. Kazemier and M. Haak and E. Pajkrt and B. Mol and C. D. Groot},
  journal={Expert Review of Obstetrics \& Gynecology},
Preterm birth is the most important cause of perinatal morbidity and mortality worldwide, and ranks among the top 10 of global causes of burden of disease. Since treatment of threatened preterm delivery has limited effectiveness, the focus is on primary and secondary prevention. Identification of risk indicators in early pregnancy provides the opportunity for preventive measures. To determine the potential impact of individualized risk indicators on the prediction of preterm birth, we reviewed… Expand
Routine second trimester cervical length screening in low risk women identified women at risk of a ‘very’ preterm birth but did not reduce the preterm birth rate: a randomised study from India
A routine second trimester CL measurement in low risk women did not reduce the PTB rate, however, screening for a short CL helped to identify two primigravidas at risk for a ’very’ PTB. Expand
Risk Factors for Preterm Labor among Women Attending El Shatby Maternity University Hospital, Alexandria, Egypt
A large number of factors have been identified to be associated with preterm birth (PTB) and several factors have be identified to been associated with several factors. Expand
McDonald versus modified Shirodkar rescue cerclage in women with prolapsed fetal membranes
The effects of the McDonald and modified Shirodkar cerclage procedures on prolonging pregnancy and improving the live birth rate were similar and either technique can be applied to prevent neonatal loss due to advanced prematurity. Expand


Maternal obesity and risk of preterm delivery.
In Sweden, maternal overweight and obesity during pregnancy were associated with increased risks of preterm delivery, especially extremely preterm Delivery, and these associations should be assessed in other populations. Expand
Epidemiology and causes of preterm birth
A short cervical length and a raised cervical-vaginal fetal fibronectin concentration are the strongest predictors of spontaneous preterm birth. Expand
Factors associated with preterm birth in Cardiff, Wales. I. Univariable and multivariable analysis.
OBJECTIVE Our purpose was to examine the associations of demographic, social, and medical factors with risk of preterm birth. STUDY DESIGN By use of the Cardiff Births Survey, a large database ofExpand
Fetal sex and preterm birth: are males at greater risk?
BACKGROUND The existence of a male excess among preterm births is interesting because it could shed light on the aetiology of preterm birth. Possible mechanisms are greater body weight, increasedExpand
Biomarkers of Spontaneous Preterm Birth: An Overview of The Literature in the Last Four Decades
Identifying similar studies on biomarkers for the prediction of PTB was a very challenging task due heterogeneities in study design, sampling issues, sampling methods, assay methods, and analyses. Expand
Ethnic disparities in the risk of adverse neonatal outcome after spontaneous preterm birth
African and South‐Asian women are at higher risk for preterm birth than European white women, however, the harmful effect of pre term birth on neonatal outcome is less severe for these women. Expand
The Preterm Prediction Study: prediction of preterm premature rupture of membranes through clinical findings and ancillary testing. The National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
The combination of short cervical length, previous preterm birth caused by preterm premature rupture of membranes, and positive fetal fibronectin screening results was highly associated with preterm delivery caused bypreterm premature rupturing of membranes in the current gestation. Expand
The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity.
Developing countries, especially those in Africa and southern Asia, incur the highest burden in terms of absolute numbers, although a high rate is also observed in North America. Expand
Prediction and early detection of preterm labor.
  • J. Iams
  • Medicine
  • Obstetrics and gynecology
  • 2003
There is no role for routine use of either cervical sonography or fibronectin to screen pregnant women for preterm birth risk, but women thought to be at increased risk may be reassured by negative test results. Expand
Development of a prognostic model for predicting spontaneous singleton preterm birth.
A multiple logistic regression model to estimate the risk of spontaneous preterm birth based on maternal and pregnancy characteristics and bootstrapping techniques were used to internally validate the model's predictive performance. Expand