Individualizing surgical treatment based on tumour response following neoadjuvant therapy in T4 primary rectal cancer.

@article{Denost2017IndividualizingST,
  title={Individualizing surgical treatment based on tumour response following neoadjuvant therapy in T4 primary rectal cancer.},
  author={Quentin Denost and Christos Kontovounisios and Shahnawaz Rasheed and Remy Chevalier and R Brasio and Maylis Capdepont and Eric Rullier and P P Tekkis},
  journal={European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology},
  year={2017},
  volume={43 1},
  pages={92-99}
}
BACKGROUND Rectal cancer involving at least one adjacent organ (mrT4b) requires multi-visceral resection to achieve clear resection margin (R0). Performing pelvic compartment preservation according to the tumour response has not been considered. This study assesses the impact of changing the surgical strategy according to tumour response in rectal cancer mrT4b. METHODS Patients with non-metastatic T4b rectal cancer at two tertiary referral centres between 2008 and 2013 were grouped as… CONTINUE READING

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  • 2017
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