Individualized therapy for persistent asthma in young children.

  title={Individualized therapy for persistent asthma in young children.},
  author={Anne R. Fitzpatrick and Daniel John Jackson and David T Mauger and Susan B{\"o}hmer and Wanda Phipatanakul and William J. Sheehan and James N. Moy and Ian M Paul and Leonard B. Bacharier and Michael D. Cabana and Ronina A. Covar and Fernando C Holguin and Robert F. Lemanske and Fernando D. Martinez and Jacqueline Ann Pongracic and Avraham Beigelman and Sachin N. Baxi and Mindy Benson and Kathryn Blake and James F Chmiel and Cori L. Daines and Michael O. Daines and Jonathan M. Gaffin and Deborah Ann Gentile and William Adam Gower and Helene M Langevin and Harsha Vardhan Madan Kumar and Jason E. Lang and Stephen C. Lazarus and J. J. G. Lima and Ngoc Ly and Jyothi Marbin and Wayne J Morgan and Ross E Myers and J Tod Olin and Stephen P. Peters and Hengameh H. Raissy and Rachel Glick Robison and Kristie R. Ross and Christine A. Sorkness and Shannon M. Thyne and Stanley J Szefler},
  journal={The Journal of allergy and clinical immunology},
  volume={138 6},
BACKGROUND Phenotypic presentations in young children with asthma are varied and might contribute to differential responses to asthma controller medications. METHODS The Individualized Therapy for Asthma in Toddlers study was a multicenter, randomized, double-blind, double-dummy clinical trial in children aged 12 to 59 months (n = 300) with asthma necessitating treatment with daily controller (Step 2) therapy. Participants completed a 2- to 8-week run-in period followed by 3 crossover periods… CONTINUE READING
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