Individualized Acupuncture for Symptom Relief in Functional Dyspepsia: A Randomized Controlled Trial.

Abstract

OBJECTIVES This study was implemented to evaluate the effect of individualized acupuncture treatment (AT) on functional dyspepsia (FD). METHODS A randomized, waitlist-controlled, two-center trial was performed. Seventy-six patients with FD were enrolled in the trial with partially individualized AT in a more realistic clinical setting performed twice a week for 15 minutes a session over 4 weeks. The participants were randomly allocated to a group receiving 8 sessions of AT for 4 weeks or a waitlist control group. After 4 consecutive weeks, the AT group was followed up without AT and the control group received the identical AT. The proportion of responders with adequate symptom relief, Nepean Dyspepsia Index (NDI), FD-related quality of life, Beck Depression Inventory, State-Trait Anxiety Inventory, Acupuncture Belief Scale, and acupuncture credibility test were assessed. RESULTS After the first 4 weeks, the proportion of responders significantly improved (59% in AT group [n = 37] versus 3% in control group [n = 39]; p < 0.001). The difference was no longer significant at 8 weeks, at which point the waitlist control group showed similar improvement after receiving AT (68% in the AT group versus 79% in the control group). Total NDI scores were significantly reduced in the AT group compared with the waitlist group (p = 0.03). Among NDI items, discomfort (p = 0.01), burning (p = 0.02), fullness after eating (p = 0.02), and burping (p = 0.02) were significantly improved in the AT group compared with the control group. No significant differences were observed between groups in other secondary variables. CONCLUSION Individualized AT adequately relieves symptoms in patients with FD, and this effect may persist up to 8 weeks.

Cite this paper

@article{Ko2016IndividualizedAF, title={Individualized Acupuncture for Symptom Relief in Functional Dyspepsia: A Randomized Controlled Trial.}, author={Seok-Jae Ko and Braden Kuo and Seul-Ki Kim and Hyangsook Lee and Jinsung Kim and Gajin Han and Juyeon Kim and Song-Yi Kim and Seungwon Jang and Jiyoung Son and Minji Kim and Hyejung Lee and Inkwon Yeo and Kwang Ro Joo and Jae-Woo Park}, journal={Journal of alternative and complementary medicine}, year={2016}, volume={22 12}, pages={997-1006} }