Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial.

@article{Ferrando2018IndividualisedPO,
  title={Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial.},
  author={C Ferrando and Marina Soro and Carmen Unzueta and F Suarez-Sipmann and J M Sequ{\'i} Canet and Juli{\'a}n Librero and Natividad Pozo and Salvador Peir{\'o} and Alicia Llombart and Irene Le{\'o}n and Inmaculada India and C{\'e}sar Aldecoa and Oscar Diaz-Cambronero and David Pesta{\~n}a and Francisco Javier Redondo and Ignacio Garutti and Jaume Balust and Jos{\'e} Ignacio Rodr{\'i}guez Garc{\'i}a and Maite Ib{\'a}{\~n}ez and Manuel Granell and Aurelio Sanabria Rodr{\'i}guez and Luc{\'i}a Gallego and Manuel de la Matta and Rafael Gamboa Gonz{\'a}lez and Andrea Brunelli and J. M. Villalba Garc{\'i}a and Lucas Rovira and Francisco Barrios and Vicente E. Torres and Samuel Hern{\'a}ndez and Estefan{\'i}a Gracia and Marta Gin{\'e} and Mar{\'i}a Garc{\'i}a and N{\'u}ria Pla Garcia and Lisset Miguel and Sergio S{\'a}nchez and Patricia Pi{\~n}eiro and Roger Pujol and Santiago Garc{\'i}a-del-Valle and Jos{\'e} Valdivia and Mar{\'i}a Jes{\'u}s Hern{\'a}ndez and Oto Padr{\'o}n and Ana Col{\'a}s and Jaume Puig and Gonzalo Azparren and Gerardo Tusman and Jes{\'u}s Monterrubio Villar and Javier Francisco Belda},
  journal={The Lancet. Respiratory medicine},
  year={2018},
  volume={6 3},
  pages={193-203}
}
BACKGROUND The effects of individualised perioperative lung-protective ventilation (based on the open-lung approach [OLA]) on postoperative complications is unknown. We aimed to investigate the effects of intraoperative and postoperative ventilatory management in patients scheduled for abdominal surgery, compared with standard protective ventilation. METHODS We did this prospective, multicentre, randomised controlled trial in 21 teaching hospitals in Spain. We enrolled patients who were aged… CONTINUE READING
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