Individual vulnerability to escalated aggressive behavior by a low dose of alcohol: decreased serotonin receptor mRNA in the prefrontal cortex of male mice.

@article{Chiavegatto2010IndividualVT,
  title={Individual vulnerability to escalated aggressive behavior by a low dose of alcohol: decreased serotonin receptor mRNA in the prefrontal cortex of male mice.},
  author={S Chiavegatto and Isabel Marian Hartmann Quadros and Guilherme Ambar and Klaus A Miczek},
  journal={Genes, brain, and behavior},
  year={2010},
  volume={9 1},
  pages={110-9}
}
Low to moderate doses of alcohol consumption induce heightened aggressive behavior in some, but not all individuals. Individual vulnerability for this nonadaptive behavior may be determined by an interaction of genetic and environmental factors with the sensitivity of alcohol's effects on brain and behavior. We used a previously established protocol for alcohol oral self-administration and characterized alcohol-heightened aggressive (AHA) mice as compared with alcohol non-heightened (ANA… CONTINUE READING
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