Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically.

@article{Buchanan1995IndividualVI,
  title={Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically.},
  author={Michael Buchanan and Stephanie J. Brister},
  journal={The Canadian journal of cardiology},
  year={1995},
  volume={11 3},
  pages={221-7}
}
OBJECTIVE To determine whether acetylsalicylic acid (ASA) inhibits hemostasis and platelet function in some individuals (ASA responders) but not in others (ASA nonresponders). DESIGN In this two-part study, part 1 was a randomized, double-blind crossover study of the effects of various single doses of ASA (80 to 1300 mg) on primary hemostasis and platelet function. Part 2 was a prospective cohort study of the effects of a chronic dose of ASA (325 mg) on primary hemostasis and platelet… CONTINUE READING

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