Individual variation in a cholinergic receptor gene modulates attention.

  title={Individual variation in a cholinergic receptor gene modulates attention.},
  author={Ivar Reinvang and Astri J. Lundervold and Helge Rootwelt and Eike Wehling and Thomas Espeseth},
  journal={Neuroscience letters},
  volume={453 3},
Cholinergic influences on attention are well documented and recent evidence indicates that genetic variation in the alpha4beta2 nicotinic receptor affects attentional networks of the brain. Several behavioral and electrophysiological studies have shown that a common polymorphism in the CHRNA4 gene (rs1044396) affects aspects of visual and auditory attentional processing. We examined genetic effects on neuropsychological measures of memory and attention in an adult life-span sample (N=488). TT… CONTINUE READING

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