Individual variability in the shape and amplitude of the BOLD-HRF correlates with endogenous GABAergic inhibition.

@article{Muthukumaraswamy2012IndividualVI,
  title={Individual variability in the shape and amplitude of the BOLD-HRF correlates with endogenous GABAergic inhibition.},
  author={Suresh D. Muthukumaraswamy and C. John Evans and Richard A. E. Edden and Richard G. Wise and Krish D. Singh},
  journal={Human brain mapping},
  year={2012},
  volume={33 2},
  pages={455-65}
}
It has previously been demonstrated that there is a negative correlation between the amplitude of the BOLD response and resting γ amino-butyric acid (GABA) concentration in visual cortex. The work here is the first to empirically characterize individual variability in the haemodynamic response functions (HRFs) in response to a simple visual stimulus and baseline GABA concentration in a population of young adult males (n = 15, aged 20-28 years). The results demonstrate that GABA concentration is… CONTINUE READING
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Statistical analysis of activation

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