Individual-specific ‘fingerprints’ of human DNA

  title={Individual-specific ‘fingerprints’ of human DNA},
  author={A. Jeffreys and V. Wilson and S. Thein},
  • A. Jeffreys, V. Wilson, S. Thein
  • Published 1985
  • Biology, Medicine
  • Nature
  • Simple tandem-repetitive regions of DNA (or ‘minisatellites’) which are dispersed in the human genome frequently show substantial length polymorphism arising from unequal exchanges which alter the number of short tandem repeats in a minisatellite1–4. We have shown previously that the repeat elements in a subset of human minisatellites share a common 10–15-base-pair (bp) ‘core’ sequence which might act as a recombination signal in the generation of these hypervariable regions5. A hybridization… CONTINUE READING
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