Individual protochordates have unique immune-type receptor repertoires

@article{Cannon2004IndividualPH,
  title={Individual protochordates have unique immune-type receptor repertoires},
  author={John P. Cannon and Robert N. Haire and Natasha Schnitker and Monique Mueller and Gary W. Litman},
  journal={Current Biology},
  year={2004},
  volume={14},
  pages={R465-R466}
}
Innate immunity is mediated by a variety of different, non-rearranging receptors and soluble molecules that recognize and facilitate the elimination of a wide range of pathogens [1]. Immunoglobulin (Ig)-type variable (V) region-containing chitin-binding proteins (VCBPs) found in the protochordate amphioxus, which diverged from the vertebrate lineage before the emergence of adaptive immunity, show structural characteristics of innate immune receptors [2]. Here we describe a very high degree of… CONTINUE READING
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