Individual fates of mesenchymal stem cells in vitro

@inproceedings{Krinner2009IndividualFO,
  title={Individual fates of mesenchymal stem cells in vitro},
  author={Axel Krinner and Martin Hoffmann and Markus L{\"o}ffler and Dirk Drasdo and Jeroen Galle},
  booktitle={BMC Systems Biology},
  year={2009}
}
BackgroundIn vitro cultivated stem cell populations are in general heterogeneous with respect to their expression of differentiation markers. In hematopoietic progenitor populations, this heterogeneity has been shown to regenerate within days from isolated subpopulations defined by high or low marker expression. This kind of plasticity has been suggested to be a fundamental feature of mesenchymal stem cells (MSCs) as well. Here, we study MSC plasticity on the level of individual cells applying… CONTINUE READING

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