Individual epigenetic variation: when, why, and so what?
@article{Gomes2008IndividualEV,
title={Individual epigenetic variation: when, why, and so what?},
author={Marcus Vin{\'i}cius Gomes and Robert A. Waterland},
journal={Nestle Nutrition workshop series. Paediatric programme},
year={2008},
volume={62},
pages={
141-50; discussion 151-5
}
}Epigenetics provides a potential explanation for how environmental factors modify the risk for common diseases among individuals. Interindividual variation in DNA methylation and epigenetic regulation has been reported at specific genomic regions including transposable elements, genomically imprinted genes and the 'inactive' X chromosomes in females. We currently have a very poor understanding of the factors that contribute to interindividual epigenetic variation. In particular, it is important…
13 Citations
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