Individual differences in prepulse inhibition of startle as a measure of individual dopamine function.

@article{Feifel1999IndividualDI,
  title={Individual differences in prepulse inhibition of startle as a measure of individual dopamine function.},
  author={David Feifel},
  journal={Behavioral neuroscience},
  year={1999},
  volume={113 5},
  pages={1020-9}
}
This study investigated whether individual differences in prepulse inhibition (PPI) of the acoustic startle reflex reflect meaningful trait differences in the function of dopaminergic substrates that regulate it. Baseline PPI of individual rats showed strong test-retest reliability across 3 consecutive test days, and there was a significant negative correlation between individual baseline PPI and both disruption of PPI produced by apomorphine and facilitation of PPI by haloperidol. The test… CONTINUE READING

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