Individual differences in novelty-seeking behavior in rats: a c-fos study

@article{Kabbaj2001IndividualDI,
  title={Individual differences in novelty-seeking behavior in rats: a c-fos study},
  author={Mohamed Kamal Kabbaj and Huda Akil},
  journal={Neuroscience},
  year={2001},
  volume={106},
  pages={535-545}
}
Novelty-seeking personality traits have been implicated in substance abuse and psychiatric disorders in humans. Novelty-seeking behaviors are also observed in rats, and individual rats exhibit substantial differences in expression of these behaviors. Thus, some rats exhibit low reactivity to novelty and high anxiety-like behavior and are termed low responders, while others are hyperresponsive to novelty and exhibit low anxiety-like behavior and are termed high responders. While we and others… CONTINUE READING
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