Individual characteristics of members of the SLC26 family in vertebrates and their homologues in insects.


The 10-member SLC26 gene family encodes anion exchangers of which SLC26A5 appears to be restricted to the outer hair cells of the inner ear. Here, the so-called prestin protein acts as a molecular motor, thought to be responsible for active mechanical amplification in the mammalian cochlea. We introduce special characteristics of SLC26A5 which may have… (More)