Individual chaperones required for Yop secretion by Yersinia.

  title={Individual chaperones required for Yop secretion by Yersinia.},
  author={Pierre Wattiau and Bridget Bernier and P Desl{\'e}e and Thomas Michiels and Guy Richard Cornelis},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={91 22},
Pathogenic yersiniae secrete anti-host proteins called Yops, by a recently discovered Sec-independent pathway. The Yops do not have a classical signal peptide at their N terminus and they are not processed during membrane translocation. The secretion domain is nevertheless contained in their N-terminal part but these domains do not resemble each other in the different Yops. We have previously shown that YopE secretion requires SycE, a 15-kDa acidic protein acting as a specific cytosolic… CONTINUE READING

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