Individual- and trial-level surrogacy in colorectal cancer.

Abstract

Two conditions must be fulfilled for an intermediate endpoint to be an acceptable surrogate for a true clinical endpoint: (1) there must be a strong association between the surrogate and the true endpoint, and (2) there must be a strong association between the effects of treatment on the surrogate and the true endpoint. We test whether these conditions are… (More)
DOI: 10.1177/0962280207081864

Topics

6 Figures and Tables