Individual Mycobacterium tuberculosis Resuscitation-Promoting Factor Homologues Are Dispensable for Growth In Vitro and In Vivo

@article{Tufariello2004IndividualMT,
  title={Individual Mycobacterium tuberculosis Resuscitation-Promoting Factor Homologues Are Dispensable for Growth In Vitro and In Vivo},
  author={J. Tufariello and W. Jacobs and J. Chan},
  journal={Infection and Immunity},
  year={2004},
  volume={72},
  pages={515 - 526}
}
  • J. Tufariello, W. Jacobs, J. Chan
  • Published 2004
  • Biology, Medicine
  • Infection and Immunity
  • ABSTRACT Mycobacterium tuberculosis possesses five genes with significant homology to the resuscitation-promoting factor (Rpf) of Micrococcus luteus. The M. luteus Rpf is a secreted ∼16-kDa protein which restores active growth to cultures of M. luteus rendered dormant by prolonged incubation in stationary phase. More recently, the Rpf-like proteins of M. tuberculosis have been shown to stimulate the growth of extended-stationary-phase cultures of Mycobacterium bovis BCG. These data suggest that… CONTINUE READING
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