Indium-silver- and zinc-silver-mediated barbier-grignard-type alkylation reactions of imines by using unactivated alkyl halides in aqueous media.

Abstract

In the presence of In or Zn/AgI/InCl(3), an efficient and practical method for the Barbier-Grignard-type alkylation reactions of simple imines by using a one-pot condensation of various aldehydes, amines (including the aliphatic and chiral version), and secondary alkyl iodides has been developed. The reaction proceeded more efficiently in water than in… (More)

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@article{Shen2008IndiumsilverAZ, title={Indium-silver- and zinc-silver-mediated barbier-grignard-type alkylation reactions of imines by using unactivated alkyl halides in aqueous media.}, author={Zhi-liang Shen and Hao-Lun Cheong and Teck Peng Loh}, journal={Chemistry}, year={2008}, volume={14 6}, pages={1875-80} }