Indirubin inhibits the migration, invasion, and activation of fibroblast-like synoviocytes from rheumatoid arthritis patients

@article{Huang2017IndirubinIT,
  title={Indirubin inhibits the migration, invasion, and activation of fibroblast-like synoviocytes from rheumatoid arthritis patients},
  author={Mingcheng Huang and Lihui Wang and Shan Zeng and Q. F. Qiu and Yaoyao Zou and Maohua Shi and Hanshi Xu and Liuqin Liang},
  journal={Inflammation Research},
  year={2017},
  volume={66},
  pages={433-440}
}
To evaluate the inhibition of indirubin in FLSs migration, invasion, activation, and proliferation in RA FLSs. The levels of IL-6 and IL-8 in cultural supernatants were measured by ELISA. RA FLS migration and invasion in vitro were measured by the Boyden chamber method and the scratch assay. Signal transduction protein expression was measured by western… CONTINUE READING