Indirect stimulation of Ca(2+)-activated Cl- current by Na+/Ca2+ exchange in rabbit portal vein smooth muscle.

@article{Leblanc1995IndirectSO,
  title={Indirect stimulation of Ca(2+)-activated Cl- current by Na+/Ca2+ exchange in rabbit portal vein smooth muscle.},
  author={Normand Leblanc and Patrick M. Leung},
  journal={The American journal of physiology},
  year={1995},
  volume={268 5 Pt 2},
  pages={H1906-17}
}
Macroscopic currents were recorded in freshly dissociated smooth muscle cells from the rabbit portal vein using the tight seal whole cell recording mode (22 degrees C). In some experiments, the indo 1 fluorescence technique was used to simultaneously monitor the changes in the concentration of free intracellular Ca2+ ([Ca2+]i; indo 1 ratio, 400/500 nm). In cells exposed to tetraethylammonium chloride (TEA) to inhibit K+ channels and 1-10 microM nifedipine or nicardipine to inhibit L-type Ca2… CONTINUE READING

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