Indirect spectrophotometric determination of BIDA, DISIDA, DTPA and MDP in labelled compounds.
@article{Walt1989IndirectSD, title={Indirect spectrophotometric determination of BIDA, DISIDA, DTPA and MDP in labelled compounds.}, author={T. N. van der Walt and P. Coetzee and P. Fourie}, journal={International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes}, year={1989}, volume={40 6}, pages={ 525-9 } }
N-(4-(n-butyl)-acetanilide)iminodiacetic acid (BIDA), N-(2,6-diisopropylacetanilide)iminodiacetic acid (DISIDA), diethylenetriaminepentaacetic acid (DTPA) and methylene diphosphonic acid (MDP) are used in labelling kits. The contents of BIDA, DISIDA or MDP of the 99mTc-labelled compounds can be determined (indirectly) spectrophotometrically with copper, eriochrome cyaanine R (ECC) and dodecylethyldimethylammonium bromide (DEDA) in a sodium barbital buffered system at pH 8.5. The calibration… CONTINUE READING
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