Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine

@article{Berendsen1997IndirectIV,
  title={Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine},
  author={Hemmie H. G. Berendsen and Chris L. E. Broekkamp},
  journal={Psychopharmacology},
  year={1997},
  volume={133},
  pages={275-282}
}
Abstract The new antidepressant mirtazapine was tested in two experimental procedures which can reveal direct or indirect 5-HT1A receptor agonistic effects. These procedures were observation for induction of lower lip retraction in rats and comparison of stimulus properties in cross-familiarization experiments with conditioned taste aversion in mice. Mirtazapine induced lower lip retraction in rats, as did the 5-HT1A receptor agonist (±)-8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT… Expand
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