Indirect hemagglutination test for detection of antibody to Rickettsia rickettsii in sera from humans and common laboratory animals.

@article{Anacker1979IndirectHT,
  title={Indirect hemagglutination test for detection of antibody to Rickettsia rickettsii in sera from humans and common laboratory animals.},
  author={Robert Anacker and Robert N Philip and Linda A Thomas and Elizabeth Casper},
  journal={Journal of clinical microbiology},
  year={1979},
  volume={10 5},
  pages={677-84}
}
Antibody production in humans and three species of laboratory animals infected with Rickettsia rickettsii was determined with the indirect hemagglutination test. Rabbits, guinea pigs, and mice were inoculated with R. rickettsii and bled at intervals. Antibody which agglutinated both fresh and glutaraldehyde-fixed sheep erythrocytes sensitized with antigen prepared either from purified rickettsiae or from infected yolk sacs was found in rabbit sera at all intervals tested (10 to 59 days… CONTINUE READING

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