Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows.

@article{Stinckens2010IndirectEO,
  title={Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows.},
  author={Anneleen Stinckens and Priyansh Mathur and Stefan Janssens and Veerle Bruggeman and Okanlawon M. Onagbesan and Martine Schroyen and Geert H J J Spincemaille and Eddy M-P Decuypere and Michel Georges and Nadine Buys},
  journal={Animal genetics},
  year={2010},
  volume={41 5},
  pages={493-8}
}
A QTL located in the paternally expressed insulin-like growth factor 2 (IGF2) gene is known to increase muscle growth and reduce fat deposition in pigs. This makes the QTL in IGF2 a good marker for use in pig breeding programmes. However, care has to be taken as it is postulated that increased leanness and lowered fat deposition may have a negative effect on the prolificacy and longevity of sows. Selection of sire and dam lines for different alleles of the mutation in the paternally imprinted… CONTINUE READING
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