Indirect control of yolk protein genes by 20-hydroxyecdysone in the fat body of the mosquito, Aedes aegypti.

@article{Deitsch1995IndirectCO,
  title={Indirect control of yolk protein genes by 20-hydroxyecdysone in the fat body of the mosquito, Aedes aegypti.},
  author={Kirk W. Deitsch and Jei S. Chen and Alexander S. Raikhel},
  journal={Insect biochemistry and molecular biology},
  year={1995},
  volume={25 4},
  pages={449-54}
}
In response to a blood meal, the fat body of the female mosquito, Aedes aegypti, begins massive production of several yolk proteins which are subsequently stored in the developing oocytes. Although 20-hydroxyecdysone (20E) is important for initiation and maintenance of expression of the yolk protein genes encoding vitellogenin (Vg) and vitellogenic carboxypeptidase (VCP), the exact nature of 20E action has not been clearly defined. A primary question is whether this hormone directly stimulates… CONTINUE READING