Indinavir and Interstitial Nephritis

  title={Indinavir and Interstitial Nephritis},
  author={Jeffrey B Kopp and Kirk D. Miller and Judith Falloon},
  booktitle={Annals of Internal Medicine},
IN RESPONSE: Sarcletti and colleagues inquire about the frequency of persistent renal dysfunction in patients with indinavir-associated flank pain and crystalluria, particularly those with renal parenchymal defects on computed tomography. In our series of 240 patients receiving indinavir, 13 patients (5%) developed such symptoms. Computed tomography was done during the acute episode in 6 patients and revealed parenchymal defects in 4 patients. Of these 4 patients, 2 have discontinued indinavir… CONTINUE READING