Indigowood root extract protects hematopoietic cells, reduces tissue damage and modulates inflammatory cytokines after total-body irradiation: does Indirubin play a role in radioprotection?

@article{You2009IndigowoodRE,
  title={Indigowood root extract protects hematopoietic cells, reduces tissue damage and modulates inflammatory cytokines after total-body irradiation: does Indirubin play a role in radioprotection?},
  author={Weir Chiang You and Wen Chuan Lin and Jia Tsz Huang and Chang Chi Hsieh},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2009},
  volume={16 12},
  pages={
          1105-11
        }
}
Radix of Isatis indigotica (indigowood root, IR) has been used in traditional medicine for its potential anti-inflammatory effect. The purpose of this study is to investigate the radioprotective effects of radiation caused damages in hematopoietic system and normal tissues in mice. A total of 57 BALB/c mice were randomized into six treatment groups: control, IR treatment (0.195, 0.585 and 1.170 g/kg, p.o. daily), L-glutamine (0.520 g/kg) and sham group. All mice except the sham group were… CONTINUE READING