Indication for differential sorting of the rat v-SNARE splice isoforms VAMP-1a and -1b.

@article{Rodepeter2017IndicationFD,
  title={Indication for differential sorting of the rat v-SNARE splice isoforms VAMP-1a and -1b.},
  author={Fiona R. Rodepeter and Susanne Wiegand and Hans-Georg L{\"u}ers and Gabriel Alejandro Bonaterra and Anson W. Lowe and Michael Bette and Ralf Jacob and Robert Mandic},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2017},
  volume={95 4},
  pages={500-509}
}
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins are essential constituents of the intracellular trafficking machinery. The variable C-terminus in the 2 rat VAMP-1 splice isoforms VAMP-1a and -1b potentially acts as a sorting signal, because similar changes at the C-terminal end of a human VAMP-1 splice isoform resulted in its sorting to mitochondria. To evaluate the differences in the subcellular localization of these two v-SNARE proteins, VAMP-1a and -1b… CONTINUE READING
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