Indian hedgehog (Ihh), one of the three mammalian hedgehog (Hh) proteins, coordinates proliferation and differentiation of chondrocytes during endochondral bone

Abstract

Much of the vertebrate skeleton arises from a cartilage template, which subsequently undergoes endochondral bone formation (Erlebacher et al., 1995; Hinchcliffe and Johnson, 1990). At the earliest stage of this process, mesenchymal cells condense to form a cartilage anlage. Initially, all chondrocytes within the anlage proliferate. Thereafter, cells in the… (More)

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Cite this paper

@inproceedings{Long2001IndianH, title={Indian hedgehog (Ihh), one of the three mammalian hedgehog (Hh) proteins, coordinates proliferation and differentiation of chondrocytes during endochondral bone}, author={Fanxin Long and Xiaoyan M. Zhang and Seth J. Karp and Yingzi Yang and Andrew P. McMahon}, year={2001} }