Indian hedgehog: a mechanotransduction mediator in condylar cartilage.

@article{Tang2004IndianHA,
  title={Indian hedgehog: a mechanotransduction mediator in condylar cartilage.},
  author={Gaoyan Tang and A. Bakr M. Rabie and Urban H{\"a}gg},
  journal={Journal of dental research},
  year={2004},
  volume={83 5},
  pages={434-8}
}
Indian hedgehog (Ihh) is a critical mediator transducing mechanical signals to stimulate chondrocyte proliferation. To clarify the cellular signal transduction pathway that senses and converts mechanical signals into tissue growth in mandibular condyle, we evaluated Ihh expression and its relation to the kinetics of replicating mesenchymal cells in condylar cartilage during natural growth and mandibular advancement. Thirty-five-day-old Sprague-Dawley rats were fitted with functional appliances… CONTINUE READING

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