Indeterminate Colitis: A Distinctive Clinical Pattern of Inflammatory Bowel Disease in Children

@article{Romano2008IndeterminateCA,
  title={Indeterminate Colitis: A Distinctive Clinical Pattern of Inflammatory Bowel Disease in Children},
  author={Claudio Romano and Annalisa Famiani and Romina Gallizzi and Donatella Comito and Valeria Ferrau' and Paolo Rossi},
  journal={Pediatrics},
  year={2008},
  volume={122},
  pages={e1278 - e1281}
}
Inflammatory bowel diseases such as Crohn disease and ulcerative colitis are frequently clinical conditions in children. Another clinical entity, indeterminate colitis, is considered a subgroup of pediatric inflammatory bowel disease. It is generally characterized by early onset in the first years of life, and clinical behavior is rapidly progressive to pancolitis. The definition of indeterminate colitis has changed over the years, but it is usually used to identify severe colitis with… Expand
Endoscopic and histologic findings in pediatric inflammatory bowel disease.
TLDR
This article reviews and attempts to correlate endoscopic and histologic findings in IBD that have particular emphasis on the pediatric population and suggests certain features are highly suggestive of either CD or UC. Expand
Inflammatory Bowel Disease-Unclassified in Children: Diagnosis and Pharmacological Management
TLDR
The therapeutic strategy is borrowed from that of UC and CD, although recent data suggest that IBDU has a lower therapeutic burden with a generally mild disease course and a good response to mesalamine. Expand
Inflammatory bowel disease in pediatric and adolescent patients: a biomolecular and histopathological review.
TLDR
The results of this review reinforce the idea that pediatric CD and UC may be further classified in various clinicopathologic entities. Expand
The Pathology of Chronic Inflammatory Bowel Disease
TLDR
The purpose of this chapter is to discuss and illustrate the pathologic manifestations and differentiating features of UC and CD in biopsies and surgical specimens, the conditions that enter into the differential diagnosis as well as features that are atypical or which can result in difficulties in diagnosis. Expand
Inflammatory bowel disease unclassified
TLDR
A series of hospitalized cases, which could not initially be classified as a subtype of IBD, are presented to try to note roles of the terms indeterminate colitis (IC) and inflammatory bowel disease unclassified (IBDU) when such a dilemma arises. Expand
Inflammatory Bowel Disease in Pediatric Age
TLDR
This review had been summarized that the incidence, clinical manifestations, practical diagnosis, and utilization of non invasive disease activity index of IBD in pediatric age in children is summarized. Expand
Nephrolithiasis as an extra-intestinal presentation of pediatric inflammatory bowel disease unclassified.
TLDR
A 9-year-old boy with isolated colitis that reached a diagnosis of IBD unclassified is reported herewith, and infliximab therapy led to a successful remission after the refractory course. Expand
[Application of the Porto criteria for the diagnosis of paediatric inflammatory bowel disease in a paediatric reference centre].
TLDR
The authors' clinical practice in IBD diagnosis has changed after the PC, and total colonoscopy with ileoscopy and performance of multiple biopsies are essential to determine extension of the inflammatory changes. Expand
Frequency of indeterminate colitis in children and adults with IBD - a metaanalysis.
TLDR
Intervention studies are required to clarify whether IC represents an IBD phenotype associated with childhood disease onset or whether the high IC frequency is due to difficulties in establishing a UC or CD diagnosis. Expand
Surgical treatment of chronic inflammatory bowel disease in children
TLDR
It may change life for CD patients and provide a reasonably good quality of life for UC after the first year and Pediatric surgeons should be able to provide adequate preoperative counseling to patients and families. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 36 REFERENCES
Indeterminate colitis in the spectrum of inflammatory bowel disease.
TLDR
The value of the category "indeterminate colitis" is discussed and it is emphasized that the term "transmural inflammation" is loosely used and that accurate definition of this criterion removes much of the difficulty from the differential diagnosis of IBD. Expand
Clinical features and pattern of indeterminate colitis: Crohn's disease with ulcerative colitis-like clinical presentation
TLDR
Overlapping of UC-like presentations was frequently observed with Crohn's colitis but less so in CD patients during their clinical course, and the basis of differentiation and treatment of IC needs more attention. Expand
Fulminant colitis in inflammatory bowel disease
TLDR
Histopathologic evaluation alone has limitations in the accurate classification of fulminant inflammatory bowel disease, and Histologically diagnosed indeterminate colitis is a heterogeneous group that may include some patients who subsequently prove to have ulcerative colitis or Crohn's disease. Expand
Clinical evolution in an outpatient series with indeterminate colitis
TLDR
A closer monitoring, as with UC patients, could be recommended only in moderate patients with indeterminate colitis, with an initial UC-like endoscopic picture. Expand
Diagnostic difficulties in inflammatory bowel disease pathology
This review summarizes some of the common diagnostic problems encountered by pathologists when evaluating patients with chronic colitis and in whom inflammatory bowel disease (IBD) is eitherExpand
Indeterminate colitis: A significant subgroup of pediatric IBD
TLDR
Indeterminate colitis is a distinct pediatric subgroup of IBD with a prevalence that is higher than that observed in adults and has an early age of disease onset and a disease that rapidly progresses to pancolitis. Expand
Overlap in the spectrum of non-specific inflammatory bowel disease--'colitis indeterminate'.
  • A. Price
  • Medicine
  • Journal of clinical pathology
  • 1978
TLDR
Case of colitis indeterminate form a small distinctive group in the spectrum of inflammatory bowel disease which is characterised by a common pattern of pathology that presents a diagnostic dilemma. Expand
Indeterminate colitis: definition, diagnosis, implications and a plea for nosological sanity
TLDR
The pathology of cases appropriately classified as indeterminate colitis and the implications of that diagnosis are described and recent advances in its pathological features, clinical management and its immunological and genetic associations are highlighted. Expand
Natural history of indeterminate colitis
TLDR
The data suggest that patients continuing with a diagnosis of indeterminate colitis in spite of careful preoperative and postoperative assessment are unlikely to show features of Crohn's disease in the long term. Expand
Frequency and clinical evolution of indeterminate colitis: a retrospective multi-centre study in northern Italy
TLDR
In this Retrospective, observational study, indeterminate colitis accounts for about 5% of initial diagnoses of IBD in northern Italy, and several clinical and demographic features can help in identifying those patients more likely to have a subsequent diagnosis of Crohn's disease and those morelikely to have an initial diagnosis of ulcerative colitis. Expand
...
1
2
3
4
...