Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication.

@article{Scannell2007IndependentSO,
  title={Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication.},
  author={Devin R. Scannell and A. C. Frank and Gavin C. Conant and Kevin P. Byrne and Megan Woolfit and Kenneth H. Wolfe},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 20},
  pages={8397-402}
}
Among yeasts that underwent whole-genome duplication (WGD), Kluyveromyces polysporus represents the lineage most distant from Saccharomyces cerevisiae. By sequencing the K. polysporus genome and comparing it with the S. cerevisiae genome using a likelihood model of gene loss, we show that these species diverged very soon after the WGD, when their common ancestor contained >9,000 genes. The two genomes subsequently converged onto similar current sizes (5,600 protein-coding genes each) and… CONTINUE READING