Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes.

@article{Ajchenbaum1993IndependentRO,
  title={Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes.},
  author={F Ajchenbaum and Kiyohiro Ando and James A. DeCaprio and James D Griffin},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 6},
  pages={4113-9}
}
Cyclins and cyclin-dependent kinases are critically involved in controlling cell cycle progression in virtually all cells. The recent identification of candidate G1 cyclins in mammalian cells has been a major advance in this field, but the exact functions of these cyclins are unknown. The expression of three D-type cyclins (D1, D2, and D3) was investigated in primary human T lymphocytes as these cells were induced to leave G0, traverse G1, and enter S phase by T cell-specific mitogens. G0 phase… CONTINUE READING

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