Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues

@article{Huang2008IndependentPS,
  title={Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues},
  author={Jeffrey T-J Huang and L Wang and Sudhakaran Prabakaran and Martina Wengenroth and Helen E. Lockstone and Dagmar Koethe and Christoph W. Gerth and Stephanie R Gross and Daniela Schreiber and Kathryn S. Lilley and Matt T Wayland and David Oxley and F. Markus Leweke and Sabine Bahn},
  journal={Molecular Psychiatry},
  year={2008},
  volume={13},
  pages={1118-1128}
}
Although some insights into the etiology of schizophrenia have been gained, an understanding of the illness at the molecular level remains elusive. Recent advances in proteomic profiling offer great promise for the discovery of markers underlying pathophysiology of diseases. In the present study, we employed two high-throughput proteomic techniques together with traditional methods to investigate cerebrospinal fluid (CSF), brain and peripheral tissues (liver, red blood cells and serum) of… CONTINUE READING
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