Independent parallel functions of p19 plant viral suppressor of RNA silencing required for effective suppressor activity

@inproceedings{Vrallyay2014IndependentPF,
  title={Independent parallel functions of p19 plant viral suppressor of RNA silencing required for effective suppressor activity},
  author={{\'E}va V{\'a}rallyay and Enikő Ol{\'a}h and Zolt{\'a}n Havelda},
  booktitle={Nucleic acids research},
  year={2014}
}
Plant viruses ubiquitously mediate the induction of miR168 trough the activities of viral suppressors of RNA silencing (VSRs) controlling the accumulation of ARGONAUTE1 (AGO1), one of the main components of RNA silencing based host defence system. Here we used a mutant Tombusvirus p19 VSR (p19-3M) disabled in its main suppressor function, small interfering RNA (siRNA) binding, to investigate the biological role of VSR-mediated miR168 induction. Infection with the mutant virus carrying p19-3M… CONTINUE READING