Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers

@inproceedings{Mikl2011IndependentLO,
  title={Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers},
  author={Martin Mikl and Georgia Vendra and Michael A Kiebler},
  booktitle={EMBO reports},
  year={2011}
}
Messenger RNA localization involves the assembly of ribonucleoprotein particles (RNPs) and their subsequent transport along the cytoskeleton to their final destination. Here, we provide new evidence that microtubule-associated protein 2 (MAP2), calcium/calmodulin-dependent protein kinase II (CaMKIIα) and β-actin RNAs localize to dendrites in distinct RNPs, which contain--unexpectedly--very few RNA molecules. The number of MAP2 molecules per particle is affected by synaptic activity and Staufen… CONTINUE READING

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