Independent effects of IgG and complement upon human polymorphonuclear leukocyte function.

@article{Goldstein1976IndependentEO,
  title={Independent effects of IgG and complement upon human polymorphonuclear leukocyte function.},
  author={Ira M. Goldstein and Howard B. Kaplan and Alan Radin and Matthias Frosch},
  journal={Journal of immunology},
  year={1976},
  volume={117 4},
  pages={1282-7}
}
Particle ingestion by polymorphonuclear leukocytes (PMN) is promoted by cell surface recognition and binding of fragments of the third component of complement (C3) and Fc regions of certain immunoglobulin (IgG) molecules. In order to determine the influence of these specific ligandsurface membrane interactions upon other PMN functions, we have employed nonphagocytosable particles (serum-treated Sepharose beads) coated with fragments of C3 and/or IgG, and have investigated whether these provide… CONTINUE READING
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