Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration.

@article{Leslie2010IndependentCV,
  title={Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration.},
  author={William D Leslie and Lisa M. Lix and H Johansson and Anders Od{\'e}n and Eugene V. McCloskey and J. A. Kanis},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2010},
  volume={25 11},
  pages={2350-8}
}
A FRAX model for Canada was constructed for prediction of osteoporotic and hip fracture risk using national hip fracture data with and without the use of femoral neck bone mineral density (BMD). Performance of this system was assessed independently in a large clinical cohort of 36,730 women and 2873 men from the Manitoba Bone Density Program database that tracks all clinical dual-energy X-ray absorptiometry (DXA) test results for the Province of Manitoba, Canada. Linkage with other provincial… CONTINUE READING

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