Independent association of HLA-DR and FCgamma receptor polymorphisms in Korean patients with systemic lupus erythematosus.

@article{Lee2003IndependentAO,
  title={Independent association of HLA-DR and FCgamma receptor polymorphisms in Korean patients with systemic lupus erythematosus.},
  author={H S Lee and Young Hwa Chung and Tai Gyu Kim and Tae Hwan Kim and Jae Bum Jun and Sung Soo Jung and S C Bae and Dae Hyun Yoo},
  journal={Rheumatology},
  year={2003},
  volume={42 12},
  pages={1501-7}
}
OBJECTIVES To determine the distribution of HLA-DR type and FcgammaRIIa/IIIa polymorphisms, and to analyse the combined effects of these genes for susceptibility in Korean systemic lupus erythematosus (SLE) patients. METHODS A total of 299 SLE patients meeting 1982 ACR criteria and 144 Korean disease-free controls were enrolled. Genotyping for the FcgammaRIIa 131 R/H and FcgammaRIIIa 176 F/V was performed by polymerase chain reaction (PCR) of genomic DNA using allele-specific primers. HLA… CONTINUE READING

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