Independent association between plasma leptin levels and heart rate in heart transplant recipients.

@article{Winnicki2001IndependentAB,
  title={Independent association between plasma leptin levels and heart rate in heart transplant recipients.},
  author={Mikolaj Winnicki and Bradley G. Phillips and Valentina Accurso and Philippe van de Borne and Abu Shamsuzzaman and Kalpana Patil and Krzysztof Narkiewicz and V. K. Somers},
  journal={Circulation},
  year={2001},
  volume={104 4},
  pages={384-6}
}
BACKGROUND Leptin, the protein product of the ob gene, has been linked to a faster heart rate in animal and human studies. The interaction between leptin and heart rate in the denervated heart is not known. Therefore, we studied the relationship between plasma leptin levels and heart rate in heart transplant recipients. METHODS AND RESULTS We studied 32 male patients (mean age, 56.5+/-9.3 years; range, 41 to 74 years) after orthotopic heart transplantation. All subjects underwent a physical… CONTINUE READING

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