Independent association between plasma leptin and C-reactive protein in healthy humans.

  title={Independent association between plasma leptin and C-reactive protein in healthy humans.},
  author={Abu S. M. Shamsuzzaman and Mikolaj Winnicki and Robert L. Wolk and Anna Svatikova and Bradley G. Phillips and D. Davison and Peter B. Berger and V. K. Somers},
  volume={109 18},
BACKGROUND C-reactive protein (CRP) is synthesized from the liver and is regulated by cytokines, especially interleukin-6. Leptin, the adipocyte-derived protein product of the ob gene, is related to amount of body fat. The long form of the leptin receptor resembles cytokine receptors, which include the interleukin-6 receptor. Both leptin and CRP may be increased in women, in obesity, and in inflammation, and both have been linked to cardiovascular pathophysiological processes and increased… CONTINUE READING


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