Independent appearance of anti-thymocyte and anti-RNA antibodies in NZB/NZW F1 mice.

Abstract

NZB and NZB/NZW (B/W) mice were studied for natural thymocytoxic autoantibody(NTA) and antibody to reovirus RNA by cytotoxicity and radioimmunoassay respectively.NZB mice developed NTA by 2-3 months of age. RNA antibodies appeared later if atall. NTA and anti-RNA were present in B/W mice starting at 4-5 months and increased in frequency with age. Either… (More)

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@article{Goldblum1975IndependentAO, title={Independent appearance of anti-thymocyte and anti-RNA antibodies in NZB/NZW F1 mice.}, author={Randall Goldblum and Ravi Pillarisetty and Norman Talal}, journal={Immunology}, year={1975}, volume={28 4}, pages={621-8} }