Independent and incremental value of deformation indices for prediction of trastuzumab-induced cardiotoxicity.

Abstract

BACKGROUND Assessment of left ventricular systolic function is necessary during trastuzumab-based chemotherapy because of potential cardiotoxicity. Deformation indices have been proposed as an adjunct to clinical risk factors and ejection fraction (EF), but the optimal parameter and optimal cutoffs are undefined. The aim of this study was to determine the… (More)
DOI: 10.1016/j.echo.2013.02.008

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