Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality.
@article{Stack2013IndependentAC, title={Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality.}, author={Austin G. Stack and Alan Hanley and Liam F. Casserly and Cornelius J. Cronin and Ahad A. Abdalla and Thomas John Kiernan and B V Murthy and Am Hegarty and A Hannigan and Huong Thu Nguyen}, journal={QJM : monthly journal of the Association of Physicians}, year={2013}, volume={106 7}, pages={ 647-58 } }
BACKGROUND
Gout and serum uric acid are associated with mortality but their simultaneous contributions have not been fully evaluated in the general population.
PURPOSE
To explore the independent and conjoint relationships of gout and uric acid with mortality in the US population.
METHODS
Mortality risks of gout and serum uric acid were determined for 15 773 participants, aged 20 years or older, in the Third National Health and Nutrition Examination Survey by linking baseline information…
118 Citations
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Targeting sUA levels of <0.36 mmol/L should be a principal goal in patients with hyperuricaemia of gout in order to reduce CV events and to extend patient survival, as an independent predictor of overall and CV-related mortality.
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Association of Gout With Long‐Term Cardiovascular Outcomes Among Patients With Obstructive Coronary Artery Disease
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A clinical history of gout is associated with worse outcomes in a contemporary population of patients with obstructive coronary artery disease, suggesting that residual cardiovascular risk is not addressed by standard medical therapy.
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