Independent Evolution of Transcriptional Inactivation on Sex Chromosomes in Birds and Mammals

@inproceedings{Livernois2013IndependentEO,
  title={Independent Evolution of Transcriptional Inactivation on Sex Chromosomes in Birds and Mammals},
  author={Alexandra M. Livernois and Shafagh A. Waters and Janine E Deakin and Jennifer A Marshall Graves and Paul D. Waters},
  booktitle={PLoS genetics},
  year={2013}
}
X chromosome inactivation in eutherian mammals has been thought to be tightly controlled, as expected from a mechanism that compensates for the different dosage of X-borne genes in XX females and XY males. However, many X genes escape inactivation in humans, inactivation of the X in marsupials is partial, and the unrelated sex chromosomes of monotreme mammals have incomplete and gene-specific inactivation of X-linked genes. The bird ZW sex chromosome system represents a third independently… CONTINUE READING
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Landscape of DNA Methylation on the Marsupial X.

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CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 56 REFERENCES

Activity map of the tammar X chrmosome shos that marsupial S inactivation is incomplete and escape is stochastic

S Al Nadaf, PD Waters, E Koina, JE Deakin, KS Jordan
  • Genome Biology
  • 2010
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Expression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2012
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

A crossspecies comparison of escape from X inactivation in Eutheria: implications for evolution of X chromosome inactivation

S Al Nadaf, JE Deakin, C Gilbert, TJ Robinson, JA Graves
  • Chromosoma
  • 2012
VIEW 3 EXCERPTS