Independent Component Analysis for Noise and Artifact Removal in Three-Dimensional Polarized Light Imaging

  title={Independent Component Analysis for Noise and Artifact Removal in Three-Dimensional Polarized Light Imaging},
  author={Kai Benning and Miriam Menzel and Jan Andr{\'e} Reuter and Markus Axer},
In recent years, Independent Component Analysis (ICA) has successfully been applied to remove noise and artifacts in images obtained from Three-dimensional Polarized Light Imaging (3D-PLI) at the mesoscale (i.e., 64 $\mu$m). Here, we present an automatic denoising procedure for gray matter regions that allows to apply the ICA also to microscopic images, with reasonable computational effort. Apart from an automatic segmentation of gray matter regions, we applied the denoising procedure to… 
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